Pantelej (Serbian Cyrillic: Пaнтeлej) is a neighborhood of the city of Niš, Serbia. It is located in Niš municipality of Pantelej.
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Pantelej is located in the north-eastern outskirt of Niš. It is flat and bordered on the south by the Nišava river, on the east by the neighborhood of Durlan, and on the west by the neighborhood of Jagodin Mala.
Pantelej was named by the Church of St. Pantelejmon.
The neighborhood is mostly residential.
There is a plan of construction of a new city park in the neighborhood.